Review the neurochemical threshold model of the relation between allergy and depression. Learn about the role of noradrenaline.

Look at the clinical aspects and noradrenergic function of atypical depression. Includes results from a study on the atypical subtype.

Guide to the actions and functions of epinephrine and norepinephrine, two related hormones secreted by the medulla of the adrenal glands.

Abstract summarizes research on brain noradrenaline and the mechanisms of action of antidepressant drugs.

View an illustration of the molecular structure of the neurotransmitter norepinephrine, also known as noradrenaline.

Peruse a summary of a study which showed that mice lacking the norepinephrine transporter are supersensitive to psychostimulants.

Learn about the effects on cognition caused by pharmacological manipulations of the alpha 2-noradrenergic system.

Abstract of an article from the "Journal of Neurochemistry" on the regulation of extracellular dopamine by the norepinephrine transporter.

Discover norepinephrine's role in the regulation of alertness and the wakefulness-sleep cycle, memory and learning, and cerebral plasticity.

Abstract of "Physiology to Functionality: the Brain and Neurotransmitter Activity" reviews the monoamine hypothesis of depression.

Nonmedical resource for those suffering from Chronic Fatigue or Fibromyalgia syndromes offers a step-by-step outline of noradrenaline synthesis.

Learn about new antidepressant drugs that target the noradrenergic transmitter system, instead of the serotonergic neurotransmitter system.

Abstract on the interactions between presynaptic alpha2-autoreceptors and presynaptic inhibitory heteroreceptors on noradrenergic neurons.

Abstract of an article on the noradrenergic function in generalized anxiety disorder, major depressive disorder, and healthy subjects.

View an abstract summarizing some of the evidence which suggests that a dysfunction in the noradrenergic system plays a role in depression.